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Developing Fruits
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Chinese National
Human Genome Center, Beijing
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CHGB
has undertaken about 70 projects since founded, in which about 40 projects is
now being deployed. All these projects are kinds of National Natural Science Foundation
of China, 863, 973, National Natural Science Foundation of Beijing and cooperation
with universities, research centers, hospitals, international institutes and biomedical
companies.
All projects are focusing on below mentioned:
1. Human Genome
Plan. CHGB has taken on 1% HGP Genome Sequencing (terminal of p-arm on chromosome
3).
2. Important microbiology whole genome sequencing, such as Shigella Flexneri2a,
Leptospira Interrogans Serovar Icterhaemorrhagiae, Xanthomonas Campestris pv.Campestris.
3.
Collecting genetic resources. Up to now, CHGB has collected about 30,000 samples
which are now put into use for genomics and proteomics research.
4. Genomics
of complicated diseases, such as psychopathy£¬neuropathy£¬cancer, cardiovascular
diseases, diabetes mellitusӣ
5. Identification and functional research of hereditary
disease genes. CHGB has identified mutant DSPP gene of hereditary opalescent dentin,
gene of childhood of absence epilepsy, gene of dilated cardiomyopathy, gene of
erythermalgia cooperating with hospitals.
6. Functional genomics
7. Structural
genomics
8. Proteomics, such as cardiovascular diseases, auto-immune diseases.
9.
SNP analysis of important diseases
10. Bioinformatics
11. Gene drug screening.
CHGB uses siRNA technique to found drug screening platform, at the same time,
screens drug targets on functional genomics platform.
12. Researching and developing
DNA/RNA techniques.