22 potential human novel protein-coding genes were identified through CGI from human fetal hippocampus ESTs database. The CDS length indicates the amino acid residuals, which were extracted by the ESTScan program. The different color boxes represent distinct homology with model organisms according to their identity rate of high score pairment (HSP). The four types of black-and-white shadings indicate the different identity rate. ▉: 80-100%; ▉: 50-80%; ▉: 25-50%; ▉: 0-25%. R. Rattus norvegicus; C. Caenorhabditis elegans; D. Drosphila melanogaster; A. Arabidopsis thaliana. The EST BM174930 is a homolog of Gallus, with identity rate 75%. The EST BM174907 is a homolog of Macaca fascicularis, with identity rate 99%.